Beware: Cholesterol-Lowering Drugs Will Soon be Prescribed for Children

Cholesterol-lowering “statin” drugs work by inhibiting an enzyme called HMG-CoA reductase that is responsible for making cholesterol. Unfortunately, this is the same enzyme that also makes Co-enzyme Q10 (CoQ10), one of the most powerful antioxidants in our bodies. CoQ10 helps protect us from the harmful effects of free radicals that cause a multitude of health conditions, including heart disease and cancer.

Blocking the body’s ability to produce cholesterol inevitably also blocks its ability to make CoQ10. Because of this association, many experts believe that the use of cholersterol-lowering drugs over extended periods of time increases the risk of cancer. One such expert is Diana Schwarzbein, MD, an endocrinologist and author of the best-selling diet book The Schwarzbein Principle. In her book, Dr. Schwarzbein quotes several studies that support an association between these medications and cancer risk.

A recent short-term study from The Netherlands found that these drugs were “safe” and effective in children (“Simvastatin safe and effective for children with familial hypercholesterolemia” Circulation, 2002; 106: 2231-37). It is likely that physicians in this country will soon be under pressure to screen children’s cholesterol levels and prescribe medications when levels are found to be high. Since these medications are usually prescribed for life, it can be expected that children will be exposed to the highest risk of side effects from long-term use.
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NDSAIDs And Acetaminophen Associated With High Blood Pressure

Recently I was shocked to hear on the evening news that, as Americans age, most if not all of us are projected to develop high blood pressure. I asked myself how this could be, as high blood pressure is certainly not a normal part of aging.

A large-population study, performed on more than 80,000 women, sheds at least some light on this mystery. The study uncovered that common over-the-counter and prescription pain medications have a strong association with high blood pressure (Arch Intern Med, 2002; 162:2204-2208 “In addition to their antipyretic, anti-inflammatory, and pain-relieving effects, analgesics may interfere with blood pressure regulation”).

Unquestionably, pain is a part of aging in our society and many people take acetaminophen and NSAIDS on a daily basis. Now we know that this type of frequent use is not free of risk.

Although these medications provide quick relief for occasional pain, there are natural approaches that have been proven to work as well or better in the long term without nasty side effects. These include dietary supplements like glucosamine and fish oil, and herbs like Boswellia. Some of these supplements also help lower elevated blood pressure. The nature of the pain should be the determining factor in selecting the most appropriate supplement or mix of supplements.

Upper Respiratory Infections and Xylitol

Upper respiratory infections are easily the most common health concern for children and are probably among the most common in adults as well. The garden-variety cold, ear infections in children and sinus infections in adults are just a few of the forms they can take.

All of these problems begin with a local irritant, be it an allergen like pollen, a virus or bacteria. The immune system’s most immediate line of defense is to wash the irritant out by increasing drainage. This drainage is uncomfortable, so the tendency is to use antihistamines and decongestants to relieve symptoms. However, it is not often explained that these medications block the immune system’s effort to rid itself of the irritant without providing other benefits.

Often the next step in the sequence of events is a full-blown upper respiratory infection. At this point antibiotics may be the only sensible choice, although some infections might resolve through natural treatments and others spontaneously even if left untreated.
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Protein Consumption, Breast Cancer and Heart Disease

For years we have heard about the presumed dangers of eating too much protein: those who are not vegetarians eat far too much protein and this is the cause of every modern ailment from cancer to heart disease, osteoporosis and so on. However, evidence supporting this view was always scant, and many of the studies quoted in support of these theories were deeply flawed.

A new large-population study that followed more than 88,000 women over a period of 18 years could find no association between intake of animal protein and risk of breast cancer (“Meat, fish and egg intake and risk of breast cancer” Int J Cancer 2003; 104(2): 221-7).

Another large study looked for a link between animal protein and heart disease and actually found that higher consumption of protein led to decreases in risk for certain types of heart disease. This led researchers to conclude that: “replacing carbohydrates with protein may be associated with a lower risk of ischemic heart disease” (Am J Clin Nutr 1999; 70(2):221-7 and Am J Clin Nutr 2000; 71(3): 848-51 “Dietary protein and risk of ischemic heart disease in women”). It seems that the more we learn about diet, the more we find that it is sugar and starches that are the real problem.

Coral Calcium

Question: I have been hearing many good things about coral calcium. What is your opinion about this supplement and do you recommend that I take it and give it to my child?

Answer: the truth is that I have been reading the same reports and, although I was skeptical all along, I knew very little about coral calcium until I decided to do some research on this topic.

If you want to sell a calcium supplement and really make some money, you’d better find a catchy name and make some bold claims even if you can’t substantiate them. In a nutshell,
this was my original thought and I must say I haven’t seen anything to change my mind.

Coral calcium is extracted from coral reefs near Okinawa, Japan and the health claims stem from the fact that Okinawans enjoy long healthy lives and apparently consume some of these coral extracts. The fact is that we have seen this type of marketing many times before and in all likelihood the Okinawans’ good health has more to do with their active lifestyle and traditional diet than coral calcium.

A closer look reveals that coral calcium is made primarily of calcium carbonate. This is the same type of calcium found in limestone and the antacid Tums. Although there is nothing specifically wrong with calcium carbonate, it is known to be very poorly absorbed, with absorption rates as low as 5%, especially in aging individuals. Other forms of calcium, including calcium citrate, far outperform the absorption of calcium carbonate.

One claim that is made for coral calcium is that it can raise blood pH making the body more alkaline. However, pH is determined by a complex set of factors and we can’t state either that raising pH is always desirable, or that calcium will predictably raise pH. In fact, within different ranges calcium can either increase or decrease alkalinity. One good place to start to assess pH balance of the body is to obtain a comprehensive blood chemistry, something that can be done with minimal expense.

The most outrageous claim I read was that coral calcium can extend life. I’ll let you be the judge of that one. To read all about these claims you can visit www.coral-calcium-supplement.com or www.coral-calcium-supplement.net.

Arsenic In Wood Playground Equipment

Arsenic is a toxic heavy metal and a recognized risk factor for bladder and lung cancers. It is also toxic to the human brain. Exposure to arsenic can lead to mental confusion, agitation and learning impairment. It is also possible, although not fully documented, that exposure to arsenic is responsible for symptoms of ADD and ADHD in some children who have been labeled with these conditions.

Arsenic is found in small amounts in the soil, and minute quantities can be detected in fruits and vegetables, especially those sprayed with certain pesticides. The largest source of exposure to arsenic is through wood used in home construction, which is treated with an arsenic-containing pesticide. Construction workers are especially at risk.

The same type of wood has also been used to make playground sets, leading to increased exposure for children. As a population group, they may be more vulnerable to neurological damage from arsenic and other heavy metals. Children who tend to place their hands or various objects in their mouths are thought to be at greatest risk.

Although arsenic-containing wood is supposed to be gradually phased out, it is still in use. You can read more about this topic in the February 8, 2003 issue of The New York Times or online at www.nytimes.com (search the archives for “arsenic”).